Microarrays Jeopardy Template

Steps	Types	Advantages and Disadvantages	Ethics	Microarrays
100 To combine or produce hybrids of two species. What does it mean to Hybridize?	100 2 How many types of microarrays are commercially available?	100 Glass DNA microarray Which type of microarray does not require specialized equipment?	100 It is the moral principles that govern a person's behavior or the conducting of an activity What is ethics?	100 Mutations and genetic alterations can lead to various forms of diseases. What can a gene mutation lead to?
200 A control sample is a sample of healthy genes used to compare with another sample. What is a control sample?	200 Glass DNA microarrays and Oligonucleotide microarrays What are the types of microarray?	200 Glass DNA microarray Which type of microarray is cheaper?	200 Yes Do ethical concerns require much consideration?	200 To detect mutations in genes or any alterations in the DNA sequence. What is the essential function of the microarray?
300 They are separated into single-stranded molecules. What are the complementary DNA are separated into?	300 Micro spotting of complementary DNA fragments on a glass slide What is unique to the glass DNA microarrays?	300 Glass DNA microarray To which type of microarray can the phenomena known as cross-hybridization occur?	300 Yes due to its complexity and involvement in the study. Does ethics need to be considered during a study?	300 mRNA What type of RNA does this process utilize?
400 Red What colour was the control sample given in the example?	400 Referred to as a “chip” involving an oligonucleotide synthesis What is unique to the oligonucleotide microarrays?	400 Oligonucleotide microarray Which microarray costs more?	400 Yes as it allows for researchers to be able to properly address them and possibly do something about it. Should there be discussions about the possible implications of the use of microarrays?	400 A microarray is a research apparatus that is used to recognize the expression of thousands of genes at the same time. What is a microarray?
500 First, the mRNA sample is isolated. Then the synthesis of complementary DNA, chains begins with addition primers. What are the first two steps of the microarray?	500 The size of printed DNA fragments, the methods of printing upon spots within the chip alongside data images generated What is the difference between the two types of microarray?	500 Refer to slides for possible answers What is an advantage and disadvantage for Oligonucleotide microarrays?	500 Informed consent Privacy Discrimination Ethic and population impact Clinical utility Name one of the possible social implications	500 Each of these chips contains many short synthetic, single-stranded DNA sequences which make up a normal gene alongside many potential mutations that the gene could be exposed to. What is a microarray chip made up of?

Microarrays

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