Anatomy & Physiology Neurotransmission Neurotransmitters Prevalence of ADHD Mydayis Clinical Studies
100
What is the brain and spinal cord?
The CNS is made up of these 2 areas of the body
100
What is threshold?
Once a neuron reaches a certain voltage, called a ______________, the cell will fire an action potential.
100
What are amino acids, biogenic amines and acetylcholine?
Name the 3 types of small molecule neurotransmitters.
100
What is 4.4 million or 9.2% - 10.7%?
Approximately ________ million children and adolescents in the US have been diagnosed with ADHD, or _________ percent?
100
What is beginning at 2 hours up to 16 hours post-dose?
This is the duration of treatment effect of Mydayis in adolescents, as determined by Study 202.
200
What is the limbic system?
This is closely linked to emotional behaviors and disorders, particularly involuntary motor and visceral reactions.
200
What is negative?
Neurons have a _____________________ resting potential.
200
What are dopamine, norepinephrine, epinephrine, serotonin and histamine.
Name the 5 biogenic amines.
200
What is 10.4 million or 4.4%?
Approximately ________ million adults in the US have been diagnosed with ADHD, or _________ percent?
200
What is beginning at 2 hours up to 16 hours post-dose?
This is the duration of treatment effect of Mydayis 50mg in adults, as determined by Study 201.
300
What is the prefrontal cortex (PFC)?
ADHD is a neurobiologic disorder thought to be associated with alterations in this area of the brain.
300
What are neurotransmitters?
These are released when an action potential reaches the presynaptic terminal. They then cross the synapse to bind to receptors on the post-synaptic neuron.
300
What are glutamate and GABA?
This is the major excitatory neurotransmitter in the CNS; this is the major inhibitory neurotransmitter.
300
What is 50-66%?
Childhood ADHD persists into adulthood what percent of the time?
300
What is ADHD-RS total score?
What was the primary efficacy measure for all double-blind Phase 3 Mydayis trials?
400
What are the thalamus and hypothalamus?
These are the most important parts of the diencephalon.
400
What is the synaptic cleft (synapse)?
This is the space between pre- and post-synaptic neurons and is specialized for release and reception of chemical transmitters.
400
What is the locus coeruleus?
The majority of norepinephrine is located here in the brain.
400
What is 76%?
Heritability of ADHD is estimated at...
400
What is Study 306?
This trial supports the use of Mydayis 12.5mg and 37.5mg once daily in the treatment of adult ADHD.
500
What are working memory, behavioral inhibition, attention and impulsivity?
The prefrontal cortex performs these 4 executive functions.
500
What are reuptake, enzyme degradation and diffusion?
Neurotransmitters are cleared from the synapse these 3 ways.
500
What is moderate?
_________________ levels of DA and NE activity provide optimal prefrontal functioning.
500
What is 32%?
The MTA study showed __________% of children have ADHD alone.
500
What is 12.5mg?
This was the starting dose for all adolescents in dose-optimization Study 305.






ADHD Disease State Education

Press F11 for full screen mode



Limited time offer: Membership 25% off


Clone | Edit | Download / Play Offline