Which of the following phases constitute the course of drug action from dose to effect?
1. Drug administration
2. Pharmacognosy
3. Pharmacokinetic
4. Pharmacodynamic

A metered dose inhaler of salmeterol delivers?

In addition to nitric oxide, which of the following inhalational agents have been approved by
the U.S. Food and Drug Administration for the treatment of pulmonary hypertension?
1. Treprostenil
2. Epoprostenol
3. Iloprost
4. Alprostadil

Which of the following are indications for the use of acetylcysteine (Mucomyst)?
1. Treatment of acetaminophen overdose
2. Treatment of excessive, viscous mucus secretions
3. Treatment of aspirin overdose
4. Treatment of purulent mucus secretions by breaking up DNA

Which of the following explains how acetylcysteine (Mucomyst) lowers the viscosity of
mucus?
a. Breaking down DNA
b. Increasing the osmolarity of the mucus and pulling water into it
c. Changing the pH of the mucus, causing it to break down
d. Substituting its sulfhydryl group for disulfide bonds and breaking a portion of the
bond forming the gel structure

Which of the following are true regarding glucocorticoids?
1. They work through activation of intracellular receptors.
2. Relief is immediate.
3. Daily compliance is essential to controlling inflammation in asthma.
4. They work in a similar fashion to adrenergic bronchodilators.

Which of the following devices are most commonly used to deliver aerosols by the inhalation
route?
1. Small particle aerosol generator
2. Metered dose inhaler
3. Small volume nebulizer
4. Soft-mist inhaler

Adrenergic bronchodilators improve flow rates for which of the following diseases?
1. Asthma
2. Acute bronchitis
3. Chronic bronchitis
4. Pulmonary fibrosis

Ipratropium bromide should be used with precaution in which of the following
diseases/conditions?
1. Prostatic hypertrophy
2. Urinary retention
3. Kidney stones
4. Glaucoma

When administering acetylcysteine (Mucomyst), the respiratory therapist should be
particularly focused on which of the following potential adverse effects?
1. Incompatibility with certain antibiotics when administered together
2. Blurred vision
3. Bronchospasm
4. Airway obstruction due to rapid liquefaction of mucus

Which of the following are considered nonsteroidal antiasthma drugs?
1. Cromolyn-like agents
2. Leukotriene modifiers
3. Anti-IgE agents
4. Anti-IgA agents

Which one or more of the following devices are used in combination with metered dose
inhaler (MDI) therapy to reduce the need for hand-breathing coordination and oropharyngeal
impaction of aerosolized drugs?
1. Reservoir devices
2. One-way spacers
3. Valved holding chambers
4. Drying chambers

Which of the following are LABA bronchodilators?
1. Indacaterol
2. Olodaterol
3. Albuterol
4. Salmeterol

Which of the following are mucoactive agents currently approved for inhalation in the United
States?
1. Tryptase alfa
2. Dornase alfa
3. Hyperosmolar saline
4. Mucomyst

Which of the following are side effects of dornase alfa administration?
1. Allergic reactions due to antibody production in the patient against dornase alfa
2. Chest pain
3. Rash
4. Laryngitis

Which of the following are medications contain fluticasone furoate?
1. Arnuity Ellipta
2. Breo Ellipta
3. Combivent Respimat
4. Advair Diskus

Which of the following are advantages for the treatment of the respiratory tract with inhaled
aerosols?
1. Doses are usually smaller.
2. Onset of drug action is rapid.
3. Delivered dose is consistent with each administration.
4. Systemic side effects are often fewer and less severe.

Which of the following are side effects of beta-2-selective bronchodilators?
1. Bradycardia
2. Tremor
3. Insomnia
4. Headache

Acetylcysteine (Mucomyst) is indicated in which of the following diseases?
1. Acute tracheobronchitis
2. Bronchiectasis
3. Chronic obstructive pulmonary disease (COPD)
4. Asthma

Which of the following should be assessed during the administration of mucolytic agents?
1. Breathing pattern and rate
2. Monitoring peak flow changes
3. Patient’s reaction to treatment
4. Monitoring for presence of hydrogen sulfide (a rotten egg odor), which means that the
acetylcysteine (Mucomyst) is no longer active

Which of the following are considered an aerosolized antiinfective agent?
1. Pentamidine
2. Ribavirin
3. Tobramycin
4. Amikacin

Pharmacologic control of the airway is mediated by receptors found on which of the following
structures?
1. Smooth muscle
2. Secretory cells
3. Blood vessels
4. Alveolar epithelium

What are some potential adverse effects with use of adrenergic bronchodilators?
1. Hypokalemia
2. Dizziness
3. Worsening ventilation/perfusion ratio ( )
4. Bradycardia

A 45-year-old man has a history of heart failure and is diagnosed with pulmonary arterial
hypertension. Initially, he is prescribed treprostinil (Tyvaso) 3 breathes (18 mcg) per
treatment session via the Tyvaso Inhalation System. Upon first administration, the patient
feels nauseated, throat irritation, muscle pain, and experiences flushing. What is the best next
course of action?

Which of the following are available formulation strength for fluticasone propionate (Flovent)
by metered dose inhaler?
1. 44 mcg/puff
2. 110 mcg/puff
3. 220 mcg/puff
4. 250 mcg/puff

When administering aerosolized pentamidine, what should the respiratory care practitioner
do?
1. Use a nebulizer that produces particles in the 1- to 2-μm mean mass aerodynamic diameter
(MMAD) range.
2. Use a nebulizer system with one-way valves and scavenging expiratory filters.
3. Provide isolation and an environmental containment system.
4. Screen patients for human immunodeficiency virus (HIV).