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Definitions True or False HIV Infection Case Study Miscellaneous
100
Retrovirus
Virus that uses an RNA genome to direct synthesis of a DNA intermediate that inserts into the host cell chromosome.
100
False, HIV can infect macrophages and dendritic cells as well.
HIV only infects CD4 T cells.
100
2-15 years
How long can clinical latency last for?
100
They inhibit reverse transcriptase, so that viral cDNA cannot be made from HIV's RNA genome.
Briefly, what do the drugs zidovudine, lamivudine, and efavirenz do?
100
HIV becomes resistant to these drugs because it mutates so quickly.
Why does HIV quickly become resistant to anti-retroviral drugs?
200
When your CD4 T cell count falls below 200 cells per microliter of blood or when you develop one or more opportunistic illnesses, regardless of your CD4 count
At what point does HIV turn into AIDS?
200
False, HIV-1 is more virulent and the principle cause of AIDS in most countries. HIV-2 is less virulent, causes a slower progression of AIDS, and is more confined to West Africa and Asia.
HIV-2 is more virulent and the principle cause of AIDS in most countries.
200
- Meningitis
- Encephalitis
- Pneumonia
- Tuberculosis
- Kaposi's sarcoma
- Non-Hodgkin's lymphoma
-B cell lymphoma
Name two types of opportunistic infections AIDS patients commonly become infected with.
200
Pediatric AIDS deals with an HIV infection that runs a more rapid course because infants have a naive adaptive immune system when they're born and are not able to fight off the virus. Adult exhibit a slower progression of AIDS because they have a fully de
What is the difference between pediatric and adult AIDS?
200
Acquired Immune Deficiency Syndrome
What does AIDS stand for?
300
Acute viremia
An HIV specific immune response.
300
True
Some people have natural protection to HIV due to a deletion of their CCR5 gene.
300
- Blood
- Semen
- Vaginal fluid
- Breast milk
Name two bodily fluids HIV can be transmitted by.
300
- Anti-HIV antibodies
- HIV specific TH1 T cells and cytotoxic CD8 T cells
- Mutations in the co-receptor (CCR5) used by HIV
- specific HLA allotypes that allow for a strong immune response
Name one way in which the immune systems tries to resist the progression of an HIV infection.
300
Human Immunodeficiency Virus
What does HIV stand for?
400
Seroconversion
When an infected person first shows detectable levels of anti-HIV antibodies in their blood serum.
400
True
HIV originated in the chimpanzee and the sooty mangabey.
400
- Sexual intercourse
- Intravenous administration of drugs with contaminated needles
- Breast-feeding
- Transfusion of human blood/components from HIV-infected donors
Name two ways HIV is commonly spread.
400
ELISA and Western Blot.
What assays can test for HIV?
400
The structure of their CD4 molecule is different, and so HIV cannot insert its RNA into their cells.
Why are monkeys immune to the HIV virus?
500
Clinical latency
The asymptomatic period that follows infection of HIV.
500
False, clinical latency is the period where a vast number of T cells are activated to fight the HIV infection.
During the stage of clinical latency, immune response against the HIV virus is low.
500
33 million people
Roughly, how many people are currently infected with HIV?
500
They lose weight due to the release of a cytokine (TNF-alpha) which causes loss of appetite.
Why do people infected with HIV lose weight?
500
Hemophiliacs have helped us better understand AIDS because they regularly go in for blood transfusions, so scientists have been able to study how HIV affects our immune system.
Which group of people helped us better understand AIDS?






All About AIDS

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