General Characteristics of Anemias | Causes of Microcytic Anemias | Diagnosis and Clinical Presentations of Microcytic Anemias | Lab Findings in Microcytic Anemia | Treatments of Microcytic Anemias. |
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What is how do anemias present on a patient?
Angina, Pale conjunctiva and skin, Headache, Lightheadedness, weakness, fatigue and dyspnea
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What is alpha thalessemia?
Caused by gene deletions on chromosome 16
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What is Hb electrophoresis?
Diagnostic tool for both thalessemias
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What is iron studies found in iron deficiency anemia
Decreased Ferritin
Increased TIBC Decreased Serum iron Decreased % saturation |
What is splenectomy?
Treatment for patients that form tetramers called HbH
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What is "What are the 3 types of anemia?"
Microcytic, Macrocytic, Normocytic
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What is molecule that precents iron influx into the blood by blocking ferroportin?
Hepcidin
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What is hepatomegaly and splenomegaly.
Presentation that is seen in both alpha and beta thalessemia
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What is lab values for sideroblastic anemia?
Increased ferritin
Decreased TIBC Increased Iron Serum levels Increased % of iron saturation |
What is colonscopy
Treatment needed for iron deficiency anemias with an underlying GI cause
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What is the Mean Corpuscular Value?
Tells you the size (volume) of the average RBC. Equal to the volume of all RBCs divided by the number of red blood cells. Determines what type of Anemia you are dealing with
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What is sideroblastic anemia?
X-linked anemia due to defective protoporphyrin synthesis
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What is Plummer-Vinson Syndrome?
An iron deficiency anemia with esophageal webbing and atrophic glossitis; presents as anemia, dysphagia and beefy red tongue.
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What is lab findings seen in alpha thalessemia
Decreased MCV
Decreased MCH |
What is treating the underlying cause?
Iron deficiency anemia and sideroblastic anemia require this treatment before treating the anemia
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What are causes of anemia?
Increased RBC destruction
Decreased RBC production Loss of RBCs |
What is major causes of iron defiency anemia
Chronic blood loss, inadequate intake, increased demand, and decreased absorption
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What is diagnostic for sideroblastic anemia
Bone marrow biopsy
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What is microytic cells, hypochromic cells, target cells, nucleated RBCs?
Four major blood smear findings in beta thalessemia major
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What is oral supplement treatment for iron deficiency anemia?
Ferrous sulfate
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What are Beta thalassemia, alpha thalassemia, iron deficinecy anemia, sideroblastic anemia and anemia of chronic disease (1/3 of the time)?
Anemias that are classified as microcytic anemias
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What is alcoholism, B6 deficiency and lead poisoning
Acquired factors that develop into sideroblastic anemia?
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What is anemia symptoms, pica, restless leg sx, angular cheiolosis, koilonchia, and changes in stool
Six symptoms commonly seen in iron deficiency anemia
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What is Microcytic, hypochromic, anisocytosis
Increased Free erythrocyte protoporphyrin Decreased Reticulocyte count
Describes blood smear findings and CBC findings found in iron deficiency anemia.
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What is chelation therapy?
Treatment used primarily for lead poisoning and beta thalessemia
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