HMS/UA Pathway TCA Cycle Oxidative Phosphorylation and Gluconeogenesis Erythrocytes Porphyrin metabolism
100
What is cytosol
The HMS pathway occurs in the
100
What is mitochondrial matrix?
This is where the TCA cycle occurs
100
What is moving NADH across the inner mito membrane
The goal of the malate shuttle
100
What is hypoxia
The release of erythropoetin is stimulated by
100
What is liver, bone marrow
Hemoglobin synthesis occurs mainly in
200
What is UDP-Glucose.
The nitrogen-containing intermediate of the uronic acid pathway
200
What is OAA?
This TCA cycle intermediate is impermeable to the mitochondrial matrix
200
What is cyanide
This inhibits Complex IV in the ETC
200
What is the hydroxyl radical OH
This oxygen derivative is considered the most toxic
200
What is reticuloendothelial tissue
Under normal circumstances, the majirty of bilirubin production occurs here
300
What is L-Gulonactone oxidase
Primates, fish, guinea pigs, and bats lack this enzyme which prevents them from producing Vitamin C
300
What is oxidative (explain) and biosynthetic.
Functions of the TCA cycle (2)
300
What is the liver and kidney
The main locations where gluconeogenesis occurs
300
What is NADH
Methehomglbin reduction in erythrocytes requires
300
What is Delta-ALA synthase
The rate limiting enzyme in heme biosythesis
400
What is G6PDH
The rate limiting enzyme of the oxidative phase of the HMS pathway
400
What is isocitrate+NAD+------->alpha kg+NADH
This reaction is the rate-limiting step in the TCA cycle
400
What is OAA -------PEP carboxykinase-----> PEP
This is the rate limiting step in gluconeogenesis
400
What is salvage pathway
Purine nucleotides are conserved through this
400
What is hepatic
This kind of jaundice is caused by liver diseases
500
What is insulin (stimulated) and NADPH (negative regulation)
The oxidative phase of the HMS pathway is stimulated and regulated by
500
What is Succinyl-CoA
Thist intermediate leaks from the TCA cycle to enter the porphyrin biosynthesis
500
What is overnight fast/ increase in glucagon
Low levels of fructose 2,6-bisphosphate as a result from this induces gluconeogenesis with the use of fructose 2,6-bisphosphatase
500
What is enhanced erythrocyte turnover
PFK deficiency would be expected to result in
500
What is enterohepatic circulation
14 % of conjugated bilirubin is put into this






Biochem Exam 1

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