Psychiatric Disorders | Anti-Psychotic Agents | Anti-Depressant Agents | Drugs for Bipolar Disorder | Dental Implications of CNS Drugs |
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Schizophrenia
What is the split or loss of reality?
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First generation
First or Second generation antipsychotic agents are more likely to treat the positive symptoms than the negative symptoms of schizophrenia?
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Selective serotonin reuptake inhibitors
What category of drugs is the first-line of therapy for the treatment of major depression?
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Lithium
What is the drug of choice for the maintenance phase of bipolar depressive disorder?
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True
True or False: Patients with depression typically practice poor oral homecare, therefore need extra motivation from their oral healthcare worker.
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Bipolar disorder
What is a disorder characterized by one exhibiting alternating periods of depression and excitation?
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False
True or False: Orthostatic hypotension is an adverse reaction of second-generation anti-psychotic agents.
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Fluoxetine (Prozac)
Sertraline (Zoloft) Paroxetine (Paxil) Citalopram (Celexa) Escitalopram (Lexapro)
Name one selective serotonin reuptake inhibitor.
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Hypomania or mania
The elevated mood in bipolar depressive disorder is known as what?
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Sugarless products
Artificial saliva Fluoride Non-alcohol containing mouthwash Decaffeinated beverages
Name one suggestion to provide the patient on an antispychotic to combat the anticholinergic effect of the oral cavity.
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Depression
One having low levels of biologic factors, such as serotonin, norepinephrine, and dopamine, can lead to what disorder?
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Tardive dyskinesia
What is an irreversible adverse drug reaction of first-generation antipsychotics causing involuntary, repetitive movements of the tongue, face, and jaw?
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Suicide
According to the FDA, there is an increased risk of _________ in children, adolescents, and young adults taking antidepressants.
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Valproate
Bamazepine Lamotrigine Carbamazepine Gabapentin
Name three agents commonly used to treat bipolar disorder that are also antiepileptics.
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xerostomia &
glossitis
Name two oral adverse reactions of SSRIs and SNRIs when used to treat major depression.
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Manic depressive disorder
Patients who exhibit alternating periods of depression and excitation have what?
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Norepinephrine
What neurotransmitter is primarily acted upon by a first-generation antipsychotic medication?
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Bupropion (Wellbutrin)
Which antidepressant has been on and off the market due to an increased risk of developing seizures at a higher dose?
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NSAIDS
What class of analgesics can reduce the clearance of lithium leading to an increase in lithium levels, therefore should be prescribed with caution?
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First-generation antipsychotics
TMJ pain can be an extrapyramidal effect from the use of which class of CNS drugs?
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Positive
Is "agitation" a positive or negative effect of psychoses?
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Clozapine
Which antipsychotic can produce the adverse effect of agranulocytosis requiring the patient to get weekly blood cell count monitoring tests?
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Monoamine Oxidase Inhibitors
What class of antidepressants interact with foods such as cheeses, wines, and fish, precipitating a hypertensive crisis?
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Second-gerneration psychotics
Both long term and acute treatment of of bipolar disorder can be treated using which type of anti-psychotics?
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Tricyclic antidepressants (TCAs)
Dental local anesthetic with vasoconstricting agents must be limited to the cardiac dose for patients taking what class of medication?
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