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Overview Of The Brain Disease State Pathophysiology of MCI Diagnosis and Treatment of MCI CerefolinNAC
100
Cerebrum
The region of the brain that is most heavily involved in cognition.
100
An intermediate stage between normal cognitive decline due to aging and that of dementia. Impairments can be seen in any cognitive function(s), but must be mild enough that the activities of daily living are not interrupted.
Define MCI
100
Which region of the brain is most affected by atrophy due to MCI?
Hippocampus
100
What are approved treatments for MCI?
Cholinesterase inhibitors, NMDA agonists
100
What is CerefolinNAC NAC indicated for?
A prescription medical food for use only under the supervision of a physician for the clinical dietary management of mild cognitive impairment and is specifically formulated to meet the distinct nutritional requirements for this condition.
200
Coordinating movements and balance
What is the main function of the cerebellum?
200
Nonamnestic multiple domain MCI would apply too a patient with what?
*Impairments in attention and problem solving
200
What is NOT a result of excess ROS activity on the brain?
Increases in the mitochondrial production of antioxidants
200
What are the 4 core criteria required for a diagnosis of MCI?
Cognitive complaint
Objective evidence of cognitive impairment
Independence in performing activities of daily life
No dementia (but not normal)
200
What are the 3 components of CerefolinNAC ?
L-methlfolate, N-acetylcystene, methlcobalamin
300
Frontal, occipital, parietal, and temporal lobes
What are the regions of the cerebral cortex?
300
How do you distinguish between MCI and dementia?
MCI patients are self sufficient, dementia patients have trouble with daily activities.
300
What are the risk factors for developing MCI?
Age, depression, hypertension
300
When diagnosing MCI, which 5 cognitive domains should be assessed or impairments?
Attention, executive function, language, memory, visuospatial function
300
What is the benefit of having CerefolinNAC over folic acid?
Many people cannot convert folic acid into L-methlfolate, the active form of folate.
400
Normal changes that occur with aging
What do the decreased processing speed, decline in overall brain mass, increased vocabulary, and loss of declarative function represent?
400
What contributes to Alzheimer’s disease?
B-amyloid plaques, tangles
400
Define oxidative stress?
The disruption of equilibrium between the production of ROS and their neutralization, in which both ROS and resulting damage they inflict are self promoting.
400
Which prescription accounts for 33% of medical food prescriptions?
CerefolinNAC
400
What is the safety profile of CerefolinNAC?
CerefolinNAC is generally recognized as safe, CerefolinNAC can be safely combined with most medications, N-acetylcysteine is not recommended for the use by critically ill patients or nursing mothers. The biggest risk with folate supplementation is that it will mask vitamin B-12 deficiency.
500
Nondeclarative memory
Is riding a bike a declarative or nondeclarative memory?
500
What is most common type of dementia?
Alzheimer’s disease
500
Why is vitamin B12 important for cognitive function?
It is important for maintenance of the myelin sheaths protecting axons.
500
What are 4 supplements that are commonly used to combat cognitive decline?
Folic Acid, Fish Oil, Ginko Biloba, NAC, Perceptive, Prevagen, Vitamin B-12, Vitamin E
500
What are the contraindications for CerefolinNAC?
CerefolinNAC is contraindicated in patients with a known hypersensitivity to any of the components contained in this product.






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