Microbial Communities | Oral Biofilms | stages of polymicrobial biofilm formation | Oral Biofilm Terms | Hypothesis on Role of Bacteria toward Periodontal Destruction |
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What color do gram positive bacteria appear microscopically?
red
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What is a term for residential bacteria that are part of the normal flora in the mouth?
commensal bacteria
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What is the stage where an extracelluar polymeric substance forms to protect the microbes from phagocytosis and antibiotic treatments?
stage 3
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What is the name for the series that developed within a biofilm to direct fluid to bring nutrients and oxygen to microbes and carry away waste products?
fluid channels
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What is the name of the historical hypothesis that stated the abundance of bacteria along the gingival margin led to gingival inflammation and tissue destruction?
Nonspecific Plaque Hypothesis
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What color do gram negative bacteria appear microscopically?
purple
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What is the term for an oral biofilm that contributes to the host's nutrition, maintenance of immune system and provides cover over the mucous membrane?
symbiosis
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What is the stage where an acquired pellicle forms on a newly cleaned tooth surface for planktonic microbes to attach?
stage 1
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What is the term when geneticaly distinct bacteria attach to one another?
coaggregation
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What is the name of the historical hypothesis that stated the presence of specific bacteria in teh biofilm directly causes the tissue destruction seen in periodontitis?
Specific Plaque Hypothesis
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What amount of time does it take the acquired pellicle to form on a newly cleaned tooth surface?
within minutes
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What is term for an oral biofilm with microbial imbalance allowing pathogenic bacteria to dominate and potentially cause periodontal destruction?
dysbiosis
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What is the stage where microbes coaggregate to genetically distinct bacteria and create a steadfast grip to the tooth surface?
stage 2
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What is the term for the protective substance secreted by bacteria to protect the biofilm from phagocytosis and antibiotic treatments?
extracellular protective matrix or extracelluar polymeric substance/extracelluar slime layer
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What is the name of the current hypothesis that states that changes in the subgingival environment to dictate the specific pathogenic biofilm that causes periodontal destruction?
Ecological Plaque Hypothesis
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What amount of time does it take for microbes to produce an initial extracellular protective matrix?
6 to 12 hours
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Why is periodontal instrumentation by a dental professional necessary in the prevention of periodontal disease?
toothbrush and floss can't reach the base of periodontal pockets to disrupt pathogenic biofilm.
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What is the stage where microbes leave the community and colonize on new tooth surfaces?
stage 5
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What is term for the tail-like or leg-like extensions on bacteria that help them "swim" through fluid?
flagella
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What is the name of the current hypothesis which states a shift form beneficial to pathogenic microbes triggers the host inflammatory response; the host inflammatory response cuases the tissue destruction seen in periodontitis?
Microbial Homeostatis- Host Response Hypothesis
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What amount of time does it take for biofilm to evolve to a fully mature biofilm resistant to antibiotics?
2 to 4 days
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What spirochete is known to cause necrotizing ulcerative gingivitis?
Treponema denticola
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What is the stage where microbes cluster together to form mushroom-shaped colonies that exchange and share products to provide a favorable living environment?
stage 4
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What is term for the hair like extension on bacteria that aid in adhesion of cells to each other and tooth surfaces?
fimbriae
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What is the name of the current hypothesis which states a certain species initiate a shift from beneficial to dysbiotic microbes that trigger the host inflammatory response causing tissue destruction seen in periodontitis?
Keystone Pathogen Hypothesis
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