| Name that anemia | Peripheral Smear | Platelet Party | What doesn't kill you, makes you stronger. | Whatever I feel like asking |
|---|---|---|---|---|
|
Iron Deficiency
Which anemia has poor compliance to treatment due to unwanted side effects?
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Hereditary spherocytosis
Which disease is associated with increased osmotic fragility on peripheral smear?
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pT/INR
This test measures the EXTRINSIC pathway and may be elevated in liver disease and warfarin use.
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Thrombocytopenia, prolonged pT & aPTT, increased FSP, Increased d-dimer, decreased fibrinogen, schistocytes on peripheral smear, decreased haptoglobin, elevated bili
List 3 lab values expected in disseminated intravascular coagulation
|
discontinue heparin !!!!!!!
A patient is admitted to your service for acute diverticulitis. She is currently on 4.5g Zosyn q8h, morphine q2h prn pain, and 5000u sq heparin q8h for DVT prophylaxis. On day 3 of admission, you note a significant drop in her platelets (450k to 35k) - What is the FIRST step in management of this patient?
|
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Folic Acid Deficiency
Which anemia is associated with neural tube defects?
|
Acute Myelogenous Leukemia
What disease will have the presence of Auer Rods on peripheral smear?
|
aPTT
This test measures the INTRINSIC pathway and may be elevated in heparin use.
|
Cefriaxone and Vancomycin
A 8yoF history of SS SCD presents for evaluation of hand swelling and pain. She has a fever of 101F. MRI reveals osteomyelitis of her 3rd and 4th metacarpal. What is the most appropriate antibiotic selection for this patient?
|
Alpha thalassemia trait
A strikingly low MCV with or without mild anemia is associated with?
|
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Vitamin b12 Deficiency
Which anemia is best confirmed by serum methylmalonic acid?
|
Multiple Myeloma
What disease associated with Rouleaux formation on peripheral smear?
|
IVIG and steroids
What is the first line treatment for ITP?
|
500
A patient undergoing chemo for breast cancer has the following CBC:
WBC: 1.0k Segs: 25% Bands: 25% Calculate the ANC. |
Polycythemia Vera
This is associated with JAK2 gene mutation, pruritis, elevated hemoglobin levels, and low EPO levels
|
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Paroxysmal Nocturnal Hemoglobinuria
This disease should be suspected in any confusing cases of hemolytic anemia. Its best screening test is flow cytometry, where it will demonstrate the absence of cd59 and cd55 on RBCs.
|
G6PD Deficiency
Disease associated with Heinz bodies, bite cells, and blister cells.
|
Thrombotic Microangiopathy (HUS or TTP)
DAILY DOUBLE*** Name one disease where a platelet transfusion (in presence of low platelets) is contraindicated?
|
Hypercalcemia of malignancy
A patient with history of breast CA presents for acute confusion and abdominal pain. Her family states she has been urinating frequently over the last few days. On exam, she is notably dehydrated. EKG indicates a shortened QT interval. What is the most likely diagnosis
|
II, VII, IX, X
What are the vitamin K dependent factors?
|
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Hemoglobin H disease (alpha thalassemia)
This disease is associated with a hemolytic anemia due to hemotetramer formation.
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Beta Thalassemia
Disease where peripheral smear shows teardrop and target cells, basophilic stippling, and microcytosis
|
Von Willebrand Disease
A patient presents with gingival bleeding and menorrhagia. Labs reveal a prolonged aPTT and increased bleeding time. Fibrinogen is normal. What is the most likely diagnosis?
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Hyperuricemia, hyperphosphatemia, hyperkalemia, and hypocalcemia
Name the 4 electrolyte abnormalities associated with tumor lysis syndrome
|
Hemolytic uremic syndrome
Plasma exchange
DAILY DOUBLE ***** What is the most common cause of renal failure in pediatric patients? What is the first line treatment for that diagnosis?
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