Basic Concepts and Principles of CRRT Part 1 | Basic Concepts and Principles of CRRT Part 2 | Continuous Renal Replacement Therapies | Hybrid Therapies | Fluid Concepts |
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What is movement of fluid through a semi-permeable membrane driven by a pressure gradient called hydrostatic pressure?
Ultrafiltration
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What is forced movement of solutes with fluid or What is "solvent drag"?
Convection
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What is Slow Continuous Ultrafiltration (SCUF)?
Continuous removal of fluid from the blood in response to hydrostatic pressure as it passes across a semipermeable membrane.
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What is Prolonged Intermittent Renal Replacement Therapy?
PIRRT
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What is the % of water in an adult body?
40-60% of adult body weight
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What is the molecular adherence to the surface or interior of the membrane?
Adsorption
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What is Continuous Venovenous Hemodialysis Filtration?
CVVHDF
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What is CVVH?
Clearance is largely convective.
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What is Slow Low Efficiency Daily Dialysis?
SLEDD
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What is 60% intracellular fluid, 40% extracellular fluid?
60%, 40%
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What is the movement of solutes only from an area of higher concentration to an area of lower concentration?
Diffusion
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What are continuous renal replacement therapies?
SCUF, CVVH, CVVHD, CVVHDF
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What is CVVHD?
Clearance is largely diffusive
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What are patients that may need CRRT?
Fluid overload, AKI, Life-threatening electrolyte imbalance, 3rd degree burns, lithium overdose
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What is intravascular fluid?
7% fluid
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What is
Osmosis
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What is membrane selectivity?
Urea, creatinine, glucose, Vitamin B12, Beta 2 M are able to go through but not cytokines nor albumin
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What are convective and diffusive clearance?
The processes of clearing toxins and intermediators in CVVHDF?
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What is effluent (dialysate+ replacement fluid +patient net UF) divided by patient weight in kg?
CRRT dose
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What are the fluid types?
Isotonic, hypertonic and hypotonic
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What are the major factors affecting diffusion?
Concentration gradient, dialysate flow rate, molecular size, permeability of the membrane
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What are the major factors affecting convection?
High Membrane permeability
Molecular size Degradation of filter membrane Replacement fluid flow rate |
What is CVVHD?
Uses dialysate, does not use replacement fluid and removes fluid and some Solutes
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What is SLEDD?
Qb 100-200 mL/min; Qd of 100-300 mL/min with UF 0-500 mL/hr
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What are mechanisms that maintain fluid balance?
renin, aldosterone, ADH ANP, thirst
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