Treatment session 1&2 more questions
100
Hodgkin Lymphoma
For stage I and IIA, radiotherapy only can be applied.
Radiotherapy can also be used to treat bulky tumor masses of this disease that remain after chemotherapy
100
Flow Cytometry
The number of blasts required per 100k cells to detect disease by using this technique is 10
100
(pick 2)
Based on blood count
Morphological appearance on blood cells
Number of blast cells
Cytogenetics
Mention 2 classifications of MDS
200
AML
Besides intensive chemotherapy using cytosine arabinoside and daunorubicin, FLT3 inhibitors can be used to treat this disease
200
Chronic myeloid leukemia (CML)
A cell positive for bcr/abl rearrangement is associated with this disease
200
Epstein-Barr
Pathogenesis of Hodgkin Lymphoma includes Ig gene rearrangement and this virus genome
300
CML
Imatinib, Nilotinib, Dasatinib, Bosutinib, Ponatinib

or Tyrosine kinase inhibitors
300
Molecular studies (PCR, RT-PCR)
This detection method is more sensitive than Fluorescence in situ hybridization (FISH)
300
S: Splenic/involvement of spleen
E: localized Extranodal extension from a mass of nodes
What do the subscripts "S" and "E" mean in clinical staging of Hodgkin Lymphoma
400
MDS
After deciding low risk or high risk based on IPSS, low risk of this disease can be treated by improving marrow function, blood transfusion, and allogenic stem cell transplantation
400
Red cell precursors
Which cell precursor corresponds to Polycythaemia (rubra) vera?
400
Bone marrow failure
Organ infiltration
lymph node predominate w <20% blasts on marrow > lymphoblastic lymphoma > ALL
Clinical Features of ALL (2+1)
500
Percentage of marrow blasts
IPSS classification is based on this, type of karyotype abnormality, number and severity of cytopenias.
500
Hemopoietic stem-cell transplantation
What is the only known cure for myelofibrosis?
500
Genetic damage
Accumulation of blast cells in the bone marrow
Pathogenesis of AML (2)






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