Alzheimer's Parkinson's Multiple Sclerosis Down Syndrome Wild Card
100
What are beta amyloid plaques and neurofibrillary tangles?
Pathologies of Alzheimer's Disease
100
What is the substantia nigra?
Brain region associated with Parkinson's Disease
100
What is the myelin sheath?
MS is characterized by the deterioration of this neural component
100
What is the cause of Down Syndrome?
Trisomy 21
100
What is fluoxetine/Prozac?
Drug mentioned by Dr. Spitzer that was effective in reducing effects of PTSD
200
What is APP?
Protein that comprise plaques
200
What are stomach/GI issues?
First symptom of Parkinson's Disease, making it difficult to diagnose in early stages
200
What is genetic?
Like Huntington's Disease, MS is a _____ disorder.
200
What is Alzheimer's Disease?
The main cause of death in individuals with Down Syndrome
200
What is a syndrome?
Dementia is a _____, not a disease.
300
What is post-mortem autopsy
The only way to currently confirm diagnosis of Alzheimer's Disease
300
What is tremors/bradykinesia?
More obvious characteristic of Parkinson's Disease, making it easier to detect
300
What is the 2nd quarter of your life (around 40 yrs of age)?
The time within one's lifespan when onset of MS usually occurs.
300
What is true?
True or false: the disruption of early endosome signaling allows for early detection of Alzheimer's Disease in individuals with Down Syndrome
300
What are cortical and subcortical?
Two categories of dementia
400
What is an active lifestyle?
The most important factor in maintaining proper brain function and preventing development of Alzheimer's Disease
400
What are depression and mood disorders?
Cognitive symptoms resulting from loss of dopaminergic neurons in Parkinson's Disease
400
What is the Epstein-Barr virus?
Virus that can cause the onset of MS
400
What is an extra copy of the APP gene?
The main cause of Alzheimer's Disease in individuals with Down Syndrome
400
What is a foot shock?
Mimicked PTSD in Dr. Spitzer's mouse models
500
What is aB?
Overactive protein pathway in Alzheimer's that causes synaptic depression and development of Alzheimer's Disease
500
What is the gut microbiome/gut-brain axis?
Subsystem associated with Parkinson's Disease, focused on by guest speaker Dr. Silke Cresswell
500
What is the equator?
Place where MS is most prevalent
500
What is NGF?
Biological molecule important for survival of neurons
500
What are: Where, What, and Why?
Three critical questions in neurology, as stated by Dr. Matt Holtzman






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