| MEDzzz | One For You, Two For Me... | To Label or Not to Label | Why Can't I Sleep? | Building Blocks |
|---|---|---|---|---|
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What are Ambien (Zolpidem), Lunesta (eszopiclone), Sonata (zaleplon)?
Non-benzo hypnotics for sleep, also known as the "Z" drugs
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What is 25-100mg? (accept up to 200mg)
Usual dosing range for trazodone in mg
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What are trazodone, remeron and seroquel?
Three commonly prescribed medication for sleep that are off label
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What is mania?
This mood state causes decreased need for sleep, rather than insomnia
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What are initial, middle and terminal insomnia?
The timing of insomnia can be described in these 3 terms
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What is trazodone?
Commonly used medication for sleep, can cause priapism
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What is 6mg?
Starting dose of doxepin for treatment of middle insomnia, in mg
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What are z drugs, benzos (restoril, halcion, dalmane, prosom, doral), belsomra, rozeram, doxepin (ANY 2)
Medications with FDA indication for insomnia are these
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What is sleep apnea? (Also accept narcolepsy)
Sleep all night but don't feel rested, falling asleep all day. You may have this sleep disorder
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What are REM and non-REM sleep?
The two main types of sleep
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What are amitriptyline (or imipramine) and remeron (mirtazapine)? (or trazodone)
Two antidepressants commonly used for sleep
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What is Ambien?
10 mg is the recommended dose, 12.5 mg for the slow release formulation this drug
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What is ramelteon (rozerem)?
Melatonin is not regulated or approved by the FDA, but this drug is
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What are medications/treatments that interfere with sleep?
Steroids, theophylline, vitamin B6, bupropion and bright light share this effect
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What is NREM stage 1 sleep?
In normal sleep architecture, this sleep stage comes first
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What is melatonin?
Commonly used OTC sleep aid that can increase dreams and nightmares
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What is remeron/mirtazapine?
7.5 mg of this drug will help with sleep but more than 30mg probably won't
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What is suvorexent(belsomra)?
Orexin receptor antagonist that has FDA approval for insomnia
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What is hyperarousal?
PTSD and ADHD cause sleep problems due to this
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What are decreased REM latency and terminal insomnia? Also accept increased REM total duration or decreased slow wave sleep (SWS)
Major depression is strongly associated with these changes in sleep architecture
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What are (any 2) hydroxyzine, trazodone, amitriptyline, doxepin
Two medications used for sleep that can prolong QTc
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What is amitriptyline?
10 mg will usually help with sleep and chronic pain but not with depression
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What are tricyclic antidepressants?
Doxepin is an example of this class of medication
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What are parasomnias?
Sleepwalking, sleep paralysis are examples of this
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What is NREM sleep?
In normal sleep architecture, this type accounts for about 75% of total sleep time
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What are
1. Alpha 1 antagonism 2. Norepinephrine 3. Locus Ceruleus 1. The mechanism of action of prazosin is this
2. It is hypothesized to decrease PTSD related nightmares by decreasing activity of this neurotransmitter 3. Which is produced in this brain structure |