Throwback






Anatomy 101 It's A Chemical Thing It Does Exist! Getting From Here to To There Things That Make You Go
100
Dorsal Horn
In the processing of pain, primary afferent neurons synapse in
100
Calcium
Activation of the NMDA receptor results in an influx of this ion
100
Nociceptors
These are free nerve endings which help transduce painful stimuli into impulses
100
C fibers
Unmyelinated fibers which carry pain signals
100
Pain
An unpleasant sensory and emotional experience associated with actual or potential tissue damage
200
Lamina of Rexed
The gray matter of the spinal cord is divided into 10
200
Alogens
This group of pain producing substances can activate nociceptors
200
Brain
Unlike it's meningeal coverings, this organ does not contain nociceptors
200
Alpha-delta fibers
Sharp, well-localized pain is mediated via
200
Supraspinal level
Modulation of pain can occur peripherally, at the spinal cord level and
300
Contralateral thalamus
Second order neurons project from the dorsal horn to this structure where they synapse with third order neurons
300
Substantia gelatinosa
The primary site of action for opiates in the spinal cord
300
Cerebral cortex
This portion of the brain is the site of perception and discrete localization of pain
300
Silent nociceptors
These receptors are only activated in the presence of inflammation
300
Gate theory
Activation of large afferent fibers inhibiting WDR neurons and spinothalamic tract activity supports this theory of pain processing
400
Spinothalamic tract
Pain impulses are sent from the spinal cord to the brain via the
400
Alpha 2
In the monoamine inhibitory pathway, NE acts on these receptors to mediate an anti-nociceptive effect
400
Windup
In this phenomena, repeated stimuli of the same intensity result in exponentially increasing firing rates
400
Attention
Perception of pain involves two main components: cognition and this, which is the basis behind hypnosis and biofeedback
400
Anterior horn
Some primary afferents do not synapse in the dorsal horn, but in this region to mediate withdrawal reflexes
500
Periaquaductal gray matter
The reticular formation, nucleus raphe magnus and this structure are involved in the process of supraspinal inhibition of pain
500
Substance P
In the opiate descending inhibitory pathway, hyperpolarization of the alpha-delta and c fibers inhibits the release of
500
Referred
The convergence of visceral and somatic afferent input in laminas I and V result in this type of pain
500
Wide dynamic range
These second order neurons carry signals for both noxious and non-noxious stimuli and are involved in spinal windup
500
Receptor field expansion
Process in the dorsal horn where previously unresponsive neurons become responsive to both noxious and non-noxious stimuli
Billy Ray Cyrus
The pain in this singer's "Achy Breaky Heart" would be considered visceral pain, while being hit by a "Wrecking Ball" would likely produce a good amount of somatic pain

Pain

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