Cell Injury And Adaptation Neoplasia Dermatopathology Tumors Inflammation and Repair
100
The aspect of disease that may be genetic or acquired.
Etiology
100
A phenomenon when formation and growth of fibrous tissue is stimulated by parenchymal cells creating a fibrosis around the tumor.
Desmoplasia
100
Target-like lesions is commonly seen in:
Erythema multiforme
100
It is the ability of immune system to mold and shape immunologic properties of cell.
Cancer immunoediting
100
It induces secretion of chemokines that recruit other leukocytes.
IL7
200
What cellular adaptation is involved in Barrett esophagus?
Metaplasia
200
When a tumor develops areas of ischemic necrosis, being organized, hyperchromatic and polymorphic, with abnormally large nuclei and mitotic figures, the tumor is said to be:
Anaplastic
200
Condition where colloid or civette bodies are commonly seen
Lichen planus
200
What is the transcription factor that drives changes in gene expression that support anabolic metabolism and cell growth?
MYC
200
It cleaves C3 and C5 complement proteins, directly yielding anaphylatoxins, and release a kinin-like peptide from kininogen.
Neutral proteases
300
What bicoehmical pathway is important in physiologic muscle hypertrophy?
Phosphoinositide 3-kinase IPI3K) / AKT Pathway
300
Lack of differentiation is called
Anaplasia
300
A type of psoriasis characterized by eruptions of small papules
Guttate Psoriasis
300
What do you call the loss of adhesion to the basement membrane?
Anoikis
300
An iron-binding protein present in specific granules, and major basic protein, a cationic protein of eosinophils, which has limited bactericidal activity but is cytotoxic to many parasites.
Lactoferrin
400
Deficiency of what vitamin induces squamous metaplasia in respiratory epithelium?
Vitamin A
400
Placental epithelium serves as origin of this epithelial tumor that is benign.
Hydatidiform mole
400
Exhibits buildup of compacted stratum corneum associated with loss of normal basket weave pattern.
Ichthyosis
400
What group of proteins sense death-inducing stimuli and promote apoptosis?
BH-3 ONLY Proteins
400
It is produced by the rapid assembly and activation of a multicomponent oxidase, NADPH oxidase (phagocyte oxidase.)
Reactive oxygen species / ROS
500
What will cause cellular hypertrophy?
Increased demand
500
A tumor composed of cells or tissues belonging to more than 1 germ cell layer, sometimes all 3:
Teratoma
500
Storiform is a characteristic of which skin disorder.
Dermatofibrosarcoma protuberans
500
This anti-apoptotic protein plays a role in protecting malignant lymphoid cells.
BCL2
500
It is the most efficient bactericidal system of neutrophils.
H2O2-MPO0halide system






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