Cell Injury And Adaptation | Neoplasia | Dermatopathology | Tumors | Inflammation and Repair |
---|---|---|---|---|
The aspect of disease that may be genetic or acquired.
Etiology
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A phenomenon when formation and growth of fibrous tissue is stimulated by parenchymal cells creating a fibrosis around the tumor.
Desmoplasia
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Target-like lesions is commonly seen in:
Erythema multiforme
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It is the ability of immune system to mold and shape immunologic properties of cell.
Cancer immunoediting
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It induces secretion of chemokines that recruit other leukocytes.
IL7
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What cellular adaptation is involved in Barrett esophagus?
Metaplasia
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When a tumor develops areas of ischemic necrosis, being organized, hyperchromatic and polymorphic, with abnormally large nuclei and mitotic figures, the tumor is said to be:
Anaplastic
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Condition where colloid or civette bodies are commonly seen
Lichen planus
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What is the transcription factor that drives changes in gene expression that support anabolic metabolism and cell growth?
MYC
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It cleaves C3 and C5 complement proteins, directly yielding anaphylatoxins, and release a kinin-like peptide from kininogen.
Neutral proteases
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What bicoehmical pathway is important in physiologic muscle hypertrophy?
Phosphoinositide 3-kinase IPI3K) / AKT Pathway
|
Lack of differentiation is called
Anaplasia
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A type of psoriasis characterized by eruptions of small papules
Guttate Psoriasis
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What do you call the loss of adhesion to the basement membrane?
Anoikis
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An iron-binding protein present in specific granules, and major basic protein, a cationic protein of eosinophils, which has limited bactericidal activity but is cytotoxic to many parasites.
Lactoferrin
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Deficiency of what vitamin induces squamous metaplasia in respiratory epithelium?
Vitamin A
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Placental epithelium serves as origin of this epithelial tumor that is benign.
Hydatidiform mole
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Exhibits buildup of compacted stratum corneum associated with loss of normal basket weave pattern.
Ichthyosis
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What group of proteins sense death-inducing stimuli and promote apoptosis?
BH-3 ONLY Proteins
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It is produced by the rapid assembly and activation of a multicomponent oxidase, NADPH oxidase (phagocyte oxidase.)
Reactive oxygen species / ROS
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What will cause cellular hypertrophy?
Increased demand
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A tumor composed of cells or tissues belonging to more than 1 germ cell layer, sometimes all 3:
Teratoma
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Storiform is a characteristic of which skin disorder.
Dermatofibrosarcoma protuberans
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This anti-apoptotic protein plays a role in protecting malignant lymphoid cells.
BCL2
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It is the most efficient bactericidal system of neutrophils.
H2O2-MPO0halide system
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