Treatment | Diagnosis, S/Sx, RF | Etiologies | Monitoring | Cases! |
---|---|---|---|---|
Vancomycin or Linezolid
What are the medications that may be added on to treat if pneumonia is MRSA (+)
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IDSA
What it the entity that publishes guidelines for the treatment of pneumonia?
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Steptococcus pneumoniae
What is the most common gram positive pathogen in pneumonia?
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Fluoroquinones
Monitor for tendonitis and tendon rupture with this antibiotic.
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Pseudomonas aeruginosa
A 63 yo F with COPD has developed pneumonia. Which pathogen should you cover for that would be unlikely in someone with healthy lungs?
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Respiratory FQ alone or Macrolide + B-Lactam
What are the options for treating CAP in a hospitalized non-ICU patient?
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Chest radiography
What is the preferred method of diagnosing CAP?
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Respiratory viruses and aspiration
What are the most common non-bacterial causes of pneumonia?
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Hearing tests before, during, and after treatment
What is one monitoring parameter that aminoglycosides and vancomycin have in common?
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Azithromycin 500 mg PO on day 1 then 250 mg PO daily x4d
A 23 yo F was diagnosed with CAP and is admitted to the med surg floor. She was started on ceftriaxone 1 g IV once daily. What other abx is necessary for the pt?
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Macrolide or Doxycycline
What is the firstline treatment for outpatient CAP in a healthy patient without abx in past 3 months?
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Abx therapy in last 3 months, smoking, alcoholism
What are risk factors associated with CAP?
|
Structural lung disease, severe COPD with exacerbations, prior abx therapy
What is a risk factor for Pseudomonas?
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Includes temp ≤ 37.8øC, HR ≤ 100 beats/min, SBP ≤ 90 mmHg, O2 sat ≥ 90% ort Po2 ≥ 60 mmHg on room air, maintain oral intake, normal mental status
What are the criteria for clinical stability?
|
Double pseudomas coverage + MRSA coverage
Vancomycin IV + Levofloxacin IV + Zosyn IV
Patient with PMH of T2DM and COPD was inpatient for 7 days and was discharged 3 days ago from the hospital with oral antibiotics, but failed to pick it up from his pharmacy due to cost. Patient presents to the ED today with fever of 103.8 F, RR 26 and upon ROS crackles heard in left lower lobe. Which IV antibiotics would you use on this patient?
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Increased risk of seizures
What can happen if two B-lactams are used?
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CURB-65
What is the scoring system used to determine severity of CAP?
|
ESRD, IV drug use, prior abx therapy, prior influenza
What are risk factors for MRSA?
|
Can consume a regular/modified meal
Can tolerate at least 1 L/day of oral fluids S/sx of infection have resolved (decreasing WBC toward normal range, temperature < 100 ºF for at least 24-48 h and respiratory rate < 20 breaths/min)
What are the criteria for IV to PO switch?
|
Staphylococcus aureus
Pseudomonas aeruginosa Enteric G (-) bacilli such as Escherichia coli Acinetobacter bambini
48 year old homeless man was found unconscious on the street, with a empty bottle of vodka near him. Patient needed to be intubated and is in the ICU. Which organisms are you concerned about in this patient, and need to be covered specifically for pneumonia?
|
Piperacillin-tazobactam 4.5 g IV q6h + cefepime 2 g IV q8h + vancomycin 15 mg/kg IV
What is the regimen for a patient with HAP a high risk of mortality or prior IV abx exposure?
|
sputum culture
What is the preferred method of diagnosing HAP/VAP?
|
Acinetobacter
What is an organism known to cause HAP and VAP but not CAP?
|
Linezolid
For which abx should you monitor CBC because of bone marrow suppression?
|
Hospital-Accquired Pneumonia
A 52-year male from an ALF presents with a 2 day history of fever and productive cough. He has mild dyspnea with excertion and has pain in his right side when he takes a deep breath. Upon ROS he is found to have crackles in the right lower lung, the remainder of examination is WNL. What is this patient diagnosed with?
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