Basic Neurotransmitters + Receptors Biostatistics + Genetics Chronic “Organic” disorders Neuroanatomy + Neuroimaging ASD/ID+LD/ADHD/kiddo disorders
100
What are

MICROGLIA
This cell type secretes innate pro-infammatory cytokines (TNF-alpha and IL-1B) in patients
with inflammatory conditions that affect the brain.
100
What is

ANOVA (tests for more than two groups on a continuous variable)
Groups of patients with MDD, dysthymia, and adjustment disorder were given mood scales. This would be the most appropriate statistical analysis to compare the means of their scores.
100
What is

TRANSVERSE MYELITIS
This condition is a forerunner of MS.
100
Where is the

RIGHT PARIETAL LOBE
60 y/o right-handed M, getting lost, only writes on right half of paper. Left-sided hemi-neglect. The lesion is located here.
100
What are

MIXED AMPHETAMINE SALTS or DEXTROAMPHETAMINE
A child with ADHD fails a trial of methylphenidate. These two medications are considered the next step in pharmacotherapy.
200
What is

OBLIGATE CO-AGONIST (one half of the agonizing key)
This is the role of glycine at the NMDA receptor.
200
What is

ARYL SULFATASE
Metachromatic leukodystrophy is associated with mutation in the gene for this enzyme.
200
What is

APOLIPOPROTEIN E-4
When combined with functional neuroimaging, this biomarker is most
likely to identify geriatric pts with mild cognitive impairment most at risk for
developing Alzheimer’s disease.
200
What is a

LATERAL MEDULLARY STROKE
This event could cause a 66 y/o with HTN to develop vertigo, diplopia, nausea, vomiting, hiccups, L face numbness, nystagmus, hoarseness, ataxia of limbs, staggering gait, and tendency to fall to the left.
200
What is

SELECTIVE NOREPINEPHRINE REUPTAKE INHIBITION
This is atomoxetine’s principal mechanism of action.
300
What is the

NUCLEUS ACCUMBENS
Dopamine release is a common final event associated with reinforcing the effects of opiates, cocaine, amphetamines, nicotine, PCP, and alcohol in this structure of the brain.
300
What is

LAST OBSERVATION CARRED FORWARD
This statistical method attempts to address the effects of participants dropping out of a
study prior to completion.
300
What is

INFORMATION PROCESSING SPEED
This domain of neurocognitive function is the most likely to show decline in people over 65 years of age.
300
What is the

CEREBELLUM
26 y.o. w/HA and R-hand clumsiness for weeks. Exam shows difficulty w/rapid alternating
movements of hand, overt intention tremor on finger-to-nose, and mildly dysmetric finger
tamping. CNS intact and no papilledema. This structure of the brain is most likely damaged.
300
What is

INTELLECTUAL DISABILITY
This is the most common comorbid condition in children with autism.
400
What is

CHOLINERGIC
This neurotransmitter system is the last to mature in the CNS of children and adolescents.
400
What is

SCHIZOPHRENIA
Adolescents with velcardiofacial syndrome (chromosome 22q11 deletion syndrome) are at substantially increased risk for developing this psychiatric disorder.
400
What is

PROGRESSIVE SUPRANUCLEAR PALSY
66 y/o c/o frequent falls, several-month hx of anxiety, unwillingness to leave home. On
exam, mild impairment of vertical gaze on smooth pursuit/ saccades, mild axial rigidity &
minimal rigidity of upper extremities, along w mild slowness of movement on finger
tapping, hand opening & wrist opposition. Posture nml. Gait tentative/awkward, but w/o
shuffling, ataxia, tremor. Pt is slow in arising from a chair. This is the most likely diagnosis.
400
Where is the

HIPPOCAMPUS
In adults, this is the location of most cerebral neurogenesis.
400
What is

HYPERACTIVITY BECOMES LESS SEVERE
INATTENTION REMAINS THE SAME
ADHD has two domains of symptoms. As children grow, this usually happens to the severity of the symptoms in each domain.
500
What is

GHB
This compound increases muscle mass by increasing episodic secretion of GH.
500
What is

Z-SCORE (Z = 2.0 means the value is 2 SD from the mean, AKA p =0.05)
This measure is used to report the deviation of a value from its group mean, expressed in standard
deviation units.
500
What is

HYPOTHALAMIC HAMARTOMA
9 y/o F has 3 month h/o seemingly unprovoked bouts of laughter. Worse when not
sleeping well. Pt does not feel happy during these episodes. Started menstruating 6
months ago, and at Tanner stage 4. The diagnosis is...
500
What is

DIFFUSION WEIGHTED MRI
This MRI technique is most likely to reveal early signs of ischemic stroke.
500
What is

LANGUAGE DEVELOPMENT
(delayed in Autism, normal in Asperger's)
While there is a strong correlation between autism and Asperger's, function in this domain is a key distinguishing feature.






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