| Application | Vocabulary | Important Dates |
|---|---|---|
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What is learning the function of certain genes?
What is RNAi used for?
|
What is RNAi(RNA interference)?
What is the process through which silencing complexes bind to and destroy any mRNA complementary to them in order to suppress certain genes?
|
When were the 1990s?
When was RNAi discovered?
|
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What is hepatitis C?
What gene was the Stanford RNAi testing tested on?
|
What is a silencing complex?
What is a multiprotein complex that incorporates siRNA or miRNa to bond to and neutralize mRNA complementary to it?
|
When was 2006?
When did Andrew Fire and Craig Mello receive their Nobel Prize?
|
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What are mice?
What were the test subjects of the Stanford RNAi testing?
|
What is microRNA?
What is formed from single stranded RNAand is a more general tool for suppressing protein translation?
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When was 1996?
When was the first instance of RNA silencing in animals documented?
|
|
What is shutting down the operation of the gene?
How does RNAi try cure Huntington's disease?
|
What is siRNA(small interfering RNA)?
What is about 22 nucleotides long and is synthesized to reduce the translation of specific mRNA;s in order to reduce the synthesis of proteins.
|
When was 1993?
When was the role of miRNA in downregulating gene expression discoverd?
|
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What are ribozymes and RNA decoys?
What is RNAi therapy combined with to stop HIV?
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What is a ribozyme?
What is an RNA molecule that can act as an enzyme?
|
When was 1998?
When did Fire and Mello discover that the ability to silence the par-1(Prader-Willi/Angelman region 1) was caused by dsRNA(double-stranded RNA)?
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