Signs and Symptoms | Pathophysiology | Morbidity and Mortality | Guidelines | Interventions |
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What is fever
Cellular hyper-metabolic state that leads to increased oxygen demand
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What is septic shock
Persistent hypotension despite adequate fluid resuscitation and lactic acid >4.0
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What is blood culture
This critical laboratory test should be obtained within the first hour but should not delay further treatment
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What is systemic inflammatory response syndrome (SIRS)
Overwhelming immune response
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What is lactic acid
Blood test that indicates poor perfusion of oxygen into tissues
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What is tachycardia (>90 bpm)
Often assumed to be caused by dehydration, this objective sign often leaves one short of breath
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What is altered level of consciousness
This sign is often attributed to neurological conditions or substance abuse instead of sepsis
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What is tachypnea (RR>20)
This vital sign is often the first sign of sepsis, yet is frequently dismissed or un-noticed in initial presentation
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