Signal Tranduction Jeopardy Template

review	review	review	review	review
100 signalling cell, extracellular ligand, target cell and receptor What are the basic requirements for signal transduction	100 decreased rate if firing What type of effect does a pacemaker have on a target cell	100 true true or false a ligand can activate more than one signaling pathway	100 1. Retionol 2. liver and bloodstream 3. cystol 1. Retinoic Acid is synthesised from where and 2.where does retinol come from ( 2 places ) 3.and it diffuses into what place	100 1. P13-k 2. Ras/MAPK(Grb/SOS) 3.PLC Name the three signaling transduction pathways
200 signaling molecule What is another name for extracellular ligand	200 secretion secretion What of effect does a salivary gland have on a target cell	200 dephosphorylation recycling or lysosomal degradation and also through reactions of phosphatases at various levels what are the different ways that cessation of insulin signaling can occur through internalization of ligand /receptor	200 Thyroglobulin Thyroglobulin.What is the precursor for the thyroid hormone 2.	200 1. output stimulates its continued production .(a activates b and b activates a to continue to activate b. the example is going into labor What is the definition of positive feed back and give an example
300 plasma membrane or intracellular A receptor is also known as these two things	300 contraction What type of effect does skeletal muscle have on a target cell	300 cholesterol Steriod Hormones are derived from where	300 1. Level of circulating ligand 2. Relative number of receptors 3. Receptor affinity What are various factors that activation is governed by	300 It can terminate a signaling event . Output inhibits its continued production or activation . Limits cellular response to maintain stability Example :hypoglycemia and hyperglycemia What is the definition of a negative feed back and provide an exampleI
400 1.endocrine- molecules that travel through the blood stream and interact with distant target cells 2. Paracrine - molecules that act on nearby cells 3. autocrine - synthesising cell is also a target cell What are the different types of signaling that are secreted by molecules and what they do	400 What is a agonista substance which initiates a physiological response when combined with a receptor What is a agonist	400 in the skin Vitamin D3 is synthesized where	400 Ionotropic receptor and a membrane protein complex that includes ligand binding sites forms a pore What is a ligand gated ion channel	400 lipophilic or hydrophilic Hormones are classified as
500 1. ion channe receptors 2. G protein coupled receptors 3 enzymes coupled receptors What are the three major classes of surface receptors	500 a substance that interferes or inhibits the physiological action of another What is a antagonist	500 steroid hormones, thyroid hormones and retinoic acid can alter gene expression lipophilic hormones include what these 3 things and can alter what type of expression	500 Gs activates adenylyl cyclase Gi inhibits adenylyl cyclase , activates potassium channels Gq activates phospholipase c and activates calcium channels on ER membrane 2. second messangers Gs activates adenylyl cyclase Gi inhibits adenylyl cyclase , activates potassium channels 1.What are the g proteins and what do they do 2. They rely on what messengers to relay intracellular signals	500 gonads , thyroid , pituitary gonads , thyroid , pituitary hormones are released fro specialized cells from where

signal tranduction

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